Dr. Tanusree Sengupta
M.Sc., Ph.D.
Assistant Professor
Department Of Chemistry
Extn : 238
Education
- B.Sc., Chemistry: Scottish Church College, Calcutta University, Kolkata, 2000
- M.Sc., Chemistry: Calcutta University, Kolkata, 2002
- Ph.D. Biochemistry: Bose Institute, Jadavpur University, Kolkata, 2008
- Assistant Professor, Department of Chemistry, SSN College of Engineering, 2016-till date
- DBT-BioCARe Fellow, Department of Biotechnology, IIT Madras, 2013-2016
- Postdoctoral Research Associate, Depepartment of Biochemistry & Biophysics, UNC at Chapel Hill, USA, 2009 – 2012
- Postdoctoral fellow, Department. of Physiology and Biophysics, Case Western Reserve University, USA, 2007- 2009
- Protein purification and characterization (structural and functional)
- Peptide-lipid interaction
- Recipient of ‘Reach the World’ travel grant to present paper in ISTH (International Society on Thrombosis and Haemostasis) meeting 2022 and 2017 held in London and Berlin respectively.
- DBT-BioCARe Fellowship by Department of Biotechnology, Government of India
- CSIR-NET Fellowship, 2001 December.
- “Structural and functional characterization of R372 and E375 variants of ZPI (Protein Z-dependent Protease Inhibitor)” funded by DST, Department of Science & Technology, Govt of India (Mar 2024 – Feb 2027) in the DST-WOS category. Sanctioned amount: Rs 25.32 lakh. (ongoing)
- “Exploring Flexible UV LED for Disinfection of Secondary Treated Municipal Wastewater” funded by Shiv Nadar Foundation (2024–2027), Sanctioned amount: Rs 36.73 lakh jointly with Shiv Nadar University, Chennai. (ongoing)
- “Characterization of Novel Mutants of Human Protein Z-dependent Protease Inhibitor (ZPI): Potential Therapeutics for Hemophilia” funded by DST-SERB, Department of Science & Technology, Govt of India (Feb 2022 – Feb 2025) in the CRG (Core Research Grant) category. Sanctioned amount: Rs 60.46 lakh jointly with IIT Madras. (completed)
- “Role of PZ-ZPI anticoagulant system on COVID-19 associated coagulopathy”. Google Cloud Research credit was awarded for 365 days by Google Cloud Research Credits Program for computational work on the above-mentioned project (Jun 2021 – Jun 2022). (completed)
- “Understanding the Structure Function Relationship of the Natural Anticoagulant ZPI, a Member of Serpin Superfamily” funded by DST-SERB, Department of Science & Technology, Govt of India (Jun 2018 – Jan 2022) in the ECR (Early Career Research) category. Sanctioned amount: Rs 34.62 lakh. (completed)
- “Structural Characterization of a human serpin and its natural variants” funded by SSN Trust (Jan2019-Jan 2021). Sanctioned amount: 4.5 lakh (completed)
- Pradhan S, Mirdha L, Sengupta T, Chakraborty H. Implications of the Lipidic Ecosystem for the Membrane Binding of ApoE Signal Peptide: Importance of Sphingomyelin. ChemBioChem. 2024, 25, e202400469.
- Pradhan S, Mirdha L, Sengupta T, Chakraborty H. Phosphatidylglycerol Acts as a Switch for Cholesterol-Dependent Membrane Binding of ApoE Signal Peptide. Langmuir. 2024, 40, 8126–8132.
- Sengupta T, Luiz A, Suganthi C, Majumder S. Coagulopathy in Severe COVID-19 Patients: Causes, Concerns and Current Treatment Regimen. Acta Haematologica Polonica. 2024, 55, 13–21.
- Mirdha L, Sengupta T, Chakraborty H. Lipid composition dependent binding of apolipoprotein E signal peptide: Importance of membrane cholesterol in protein trafficking. Biophysical Chemistry. 2022, 291, 106907.
- Chellam Gayathri S, Gupta S, Suresh A, Senapati S, Sengupta T. Effect of variations in the conserved residues E371 and S359 on the structural dynamics of protein Z dependent protease inhibitor (ZPI): A molecular dynamic simulation study. Journal of Biomolecular Structure and Dynamics. 2022, 40(14), 6405–6414.
- Ongoing: 2