Dr. Guruprakash Subbiahdoss

 

Guruprakash-SubbiahdossAssociate Professor

Dr. Guruprakash Subbiahdoss  M.E., Ph. D, PDF

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Dr. Guruprakash Subbiahdoss completed his Bachelor´s in Mechanical Engineering in 2001 from Mepco Schlenk Engineering College, India and in 2005, he obtained his Master´s in Biomedical Engineering from Aachen University of Applied Sciences, Germany. In 2010, he obtained his PhD in Biomedical Engineering at the University of Groningen, The Netherlands. During his PhD, he worked on the development of in vitro methodologies based on infection models for the evaluation of biomaterials. During his post-doctoral work (2010-2012), project involves nanoparticle based strategies in combating biomaterial-associated infections.

His areas of interest focuses on understanding microbial adhesion and biofilm formation on biomaterials, interplay between pathogen-biomaterial-host and how biofilms can be prevented by exploiting new developments in nanotechnology.

Selected List of Publications

  • Busscher HJ, Van der Mei HC, Subbiahdoss G, Jutte PC, Van den Dungen J, Zaat SAJ, Schultz M, Grainger DW. Biomaterial-associated infection: Where’s the finish line in the race for the surface?. Science-Translational Medicine 2012; 4(153):153rv10.
  • Subbiahdoss G, Sharifi S, Grijpma DW, Laurent S, Van der Mei HC, Mahmoudi M, Busscher HJ. Magnetic targeting of surface-modified superparamagnetic-iron-oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci. Acta Biomater. 2012; 8: 2047-2055.
  • Wang Y, Subbiahdoss G, Swartjes J, Van der Mei HC, Busscher HJ, Libera M. Length-scale-mediated differential adhesion of mammalian cells and microbes. Adv Funct Mater 2011, DOI: 10.1002/adfm.201100659.
  • Subbiahdoss G, Kuijer R, Busscher HJ, Van der Mei HC. Mammalian cell growth versus biofilm formation on biomaterials surfaces in a post-operative contamination model in vitro. Microbiology 2010; 156: 3073-3078.
  • Subbiahdoss G, Kuijer R, Grijpma DW, Van der Mei HC, Busscher HJ. Microbial biofilm growth vs. tissue integration: “The race for the surface” experimentally studied. Acta Biomater 2009; 5: 1399-1404.